Publications
Selected Publications
Dombrovski, M., Zang, Y., Frighetto, G., Vaccari., A., Jang, HJ., Mirshahidi, P., … Card, G.M. & Zipursky, S.L.
Nature 644, 453–462 (2025). PDF
Nature 644, 453–462 (2025). PDF
We discover a new molecular principle of synaptic specificity (i.e., precise brain wiring), where levels of gene expression within a single neuronal type can fine-tune synapse numbers, enabling precise wiring of ethologically relevant neural circuits.
Dombrovski, M., Peek, M., Park, JY., … Zipursky, S.L., & Card, G.M.
Nature 613, 534–542 (2023). PDF
Nature 613, 534–542 (2023). PDF
We discover a new principle of neuronal connectivity, where synapse numbers gradually vary between neurons belonging to the same neuronal type. This enables accurate and precise transformation of object location into precise movement directions.
Other Publications
Expansion-Assisted Hybridization Chain Reaction-smFISH and Immunohistochemistry in Drosophila Brain
Mirshahidi, P., Frighetto, G., Orth, J., Vaccari, A., and Dombrovski, M. JoVE (2026).
Electrical Synapses Mediate Visual Approach Behavior
Frighetto, G., Dombrovski, M., Kurmangaliyev, Y.Z., Zipursky, S.L. and Frye, M.A. bioRxiv (2025).
A Connectome and Transcriptome Identity Switch through a Single Transcription Factor Isoform
Smolin, N., Dombrovski, M., … J., Kurmangaliyev, Y. and von Reyn, C.R. bioRxiv (2025).
Brain Wiring Determinants Uncovered by Integrating Connectomes and Transcriptomes
Yoo, J., Dombrovski, M., … Zipursky, S.L. and Kurmangaliyev, Y.Z., 2023. Current Biology (2023).
FlySeg: an Automated Volumetric Instance Segmentation Algorithm for Dense Cell Populations in Drosophila Melanogaster Nervous System
Vaccari, A. and Dombrovski, M. Proceedings of the IEEE (2023).
Critical Periods Shaping the Social Brain: A Perspective from Drosophila
Dombrovski, M. and Condron, B. BioEssays (2021).
Cooperative Foraging During Larval Stage Affects Fitness in Drosophila
Dombrovski, M., Kuhar, R., Mitchell, A., Shelton, H. and Condron, B. J Comp Phys A (2020).
A Plastic Visual Pathway Regulates Cooperative Behavior in Drosophila Larvae
Dombrovski, M., Kim, A., … Condron, B., and Yuan, Q. Current Biology (2019).
Cooperative Behavior Emerges Among Drosophila Larvae
Dombrovski, M., Poussard, L., …. Acton, S. and Condron, B. Current Biology (2017).
Mirshahidi, P., Frighetto, G., Orth, J., Vaccari, A., and Dombrovski, M. JoVE (2026).
Electrical Synapses Mediate Visual Approach Behavior
Frighetto, G., Dombrovski, M., Kurmangaliyev, Y.Z., Zipursky, S.L. and Frye, M.A. bioRxiv (2025).
A Connectome and Transcriptome Identity Switch through a Single Transcription Factor Isoform
Smolin, N., Dombrovski, M., … J., Kurmangaliyev, Y. and von Reyn, C.R. bioRxiv (2025).
Brain Wiring Determinants Uncovered by Integrating Connectomes and Transcriptomes
Yoo, J., Dombrovski, M., … Zipursky, S.L. and Kurmangaliyev, Y.Z., 2023. Current Biology (2023).
FlySeg: an Automated Volumetric Instance Segmentation Algorithm for Dense Cell Populations in Drosophila Melanogaster Nervous System
Vaccari, A. and Dombrovski, M. Proceedings of the IEEE (2023).
Critical Periods Shaping the Social Brain: A Perspective from Drosophila
Dombrovski, M. and Condron, B. BioEssays (2021).
Cooperative Foraging During Larval Stage Affects Fitness in Drosophila
Dombrovski, M., Kuhar, R., Mitchell, A., Shelton, H. and Condron, B. J Comp Phys A (2020).
A Plastic Visual Pathway Regulates Cooperative Behavior in Drosophila Larvae
Dombrovski, M., Kim, A., … Condron, B., and Yuan, Q. Current Biology (2019).
Cooperative Behavior Emerges Among Drosophila Larvae
Dombrovski, M., Poussard, L., …. Acton, S. and Condron, B. Current Biology (2017).
